MicrorarrayDetection: Detecting biological agents with DNA Micorarray
DNA-Microarrays, well known for measuring gene expression levels, can be used for detecting presence or absence of biological targets (viruses of bacteria) from hybridization patterns of oligonucleotide probes and genomic DNA of agents. Due to sequence similarity of possible targets the use of non-unique oligonucleotides becomes necessary. With use of statistical group testing and phylogenetic information about targets, even the detection of novel targets becomes viable.
For further information contact Alexander Schliep (firstname.lastname@example.org). This project is connected to the following projects: MCPD.
Members: Alexander Schliep, Alexander Schliep, Jonas Heise. Collaborators: Knut Reinert (Freie Universitaet Berlin, Algorithmic Bioinformatics), Sven Rahmann (Bielefeld University, Computational Methods for Emerging Technologies), David C. Torney (Los Alamos National Laboratory, Theoretical Biology and Biophysics (T-10)), Gunnar Klau (Centrum Wiskunde & Informatica).
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