Source:

 

@ARTICLE{Liang2005,

author = {Yu Liang and Maximilian Diehn and Nathan Watson and Andrew W Bollen and Ken D Aldape and M. Kelly Nicholas and Kathleen R Lamborn and Mitchel S Berger and David Botstein and Patrick O Brown and Mark A Israel},

title = {Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme.},

journal = {Proc Natl Acad Sci U S A},

year = {2005},

volume = {102},

pages = {5814--5819},

number = {16},

month = {Apr},

doi = {10.1073/pnas.0402870102},

url = {http://dx.doi.org/10.1073/pnas.0402870102}

}

 

Original data: http://www.ncbi.nlm.nih.gov/projects/geo/query/acc.cgi?acc=GSE4058

 

Description:

 

Glioblastoma multiforme (GBM) is the most common form of malignant glioma, characterized by genetic instability, intratumoral histopathological variability, and unpredictable clinical behavior. The authors investigated global gene expression in surgical samples of brain tumors. Gene expression profiling revealed large differences between normal brain samples and tumor tissues and between GBMs and lower-grade oligodendroglial (ODG) tumors.

 

  • Liang: 28 GBM, 6 ODG and 3 Normal.

 

Parameters used in our filter:

 

  • Liang: l=4 and  c=34